TECHNOLOGY
TECHNOLOGY
Inferior turbinate
A mucosal structure beneath the lateral wall of the nasal cavity. It regulates the temperature of inhaled air and acts as a barrier against harmful substances such as fine dust and bacteria.
1Upper lateral cartilage2Nasal septum3Inferior turbinate4External nose2Nasal septum3Inferior turbinate - 1Upper lateral cartilage
- 2Nasal septum
- 3Inferior turbinate
- 4External nose
Obstruction from hypertrophy
Nasal passage blockage due to excessive enlargement of the inferior turbinate.
Nasal congestion resulting from obstruction of the nasal cavity.
Underlying conditions
Trigger factors such as external infections or allergic rhinitis (vasomotor or hypertrophic types).
Normal
Moderate
Severe
Obstructive
Allergic rhinitis treatment market
Global market forecast 2019–2026 (unit: US$ billion)
US $6.95bn
2019
CAGR
4.20%
US $9.66bn
2026
Restraints of existing treatment
High
cost
cost
Side
effects
effects
Long
recovery
recovery
▼
RHINOS overcomes these restraints —
with the potential to become a market leader
with the potential to become a market leader
HIFU-based treatment
Non-invasive
Proven by clinical trials
What is HIFU?
High-Intensity Focused Ultrasound (HIFU) is a non-contact method that concentrates ultrasound energy at a single point to generate high temperatures.
The target tissue can be precisely destroyed while leaving the surface completely unharmed.
Anatomical Depths1Transducer2Dermis range ~2.5–3.0 mm3Subcutaneous adipose tissue4Low power density (W/cm²) leaves skin unharmed5High power density (W/cm²) destroys targeted fat~1 cm6Visible laser and light (400–750 nm)7Bi-polar RF8Near-infrared laser and light (700–1400 nm)9Mono- or uni-polar RF - 1Transducer
- 2Dermis range ~2.5–3.0 mm
- 3Subcutaneous adipose tissue
- 4Low power density (W/cm²) leaves skin unharmed
- 5High power density (W/cm²) destroys targeted fat
- 6Visible laser and light (400–750 nm)
- 7Bi-polar RF
- 8Near-infrared laser and light (700–1400 nm)
- 9Mono- or uni-polar RF
Why a non-invasive approach is needed
1Side effects & complications of invasive treatments
Because existing treatments are performed by invasive methods, there is always a risk of side effects and complications such as bleeding, inflammation and necrosis.
1Laser2Electrocautery3Rotary suction3Rotary suction ▶
Side effect 2Burden of post-procedure care & recovery
Nasal packing is required for hemostasis and absorption of secretions, together with concurrent drug treatment using anti-inflammatory drugs, antibiotics and analgesics.
1Layers of gauze soaked in petrolatum2Bayonet forceps - 1Layers of gauze soaked in petrolatum
- 2Bayonet forceps
3Infection problems due to invasive treatments
Serious infection risk during treatment — from the surgical environment, medical equipment and medical staff, as well as cross-infection between patients.
MRSA
P. aeruginosa
S. aureus
VRE
Other / no culture
Source: Yonsei Univ. Graduate School of Public Health (2006), Korea Consumer Agency cases
26.1%89 cases caused by bacterial or other microbial infection
▶
44.9%of these 89: surgical-site infection
Spine surgery
Joint replacement
Share of surgical-site infections by procedure
▼
A paradigm shift in treatment through non-invasive approaches
- Minimized side effects and complications
- Minimized bleeding and infection
- No need for nasal packing or medication
- Dramatically shortened recovery period
- Can resume daily life immediately after the procedure
1Inferior turbinateBeforeAfter - 1Inferior turbinate
